Cell dynamics and tissue mechanics during epithelial-mesenchymal transition

This project focuses on modification of cell behavior and epithelium architecture during EMT. We are interested in what drives normal epithelial growth and what changes in cell behavior are necessary and sufficient to promote EMT and cell extrusion. It combines experimental approaches using the chiken embryo, computational modelling and new strategies for image analysis.

See Ferreira et al, BioRXIv 2019.

Collaborations:

Prof. Pierre Degond - Imperial College; London, UK.

As. Prof. Sara Merino-Aceituno and Steffen Plunder (PhD Student) - University of Vienna, Austria.

Dr. Marina Ferreira - University of Helsinki, Finland.

Drs. Franck Plouraboué - Institute of Fluid Mechanics; Toulouse, France.

Funding

Other funding : Fondations RITC and Toulouse Cancer Santé