Publications
Publications de l'équipe Legube
- Arnould C, Rocher V, Finoux AL, Clouaire T, Li K, Zhou F, Caron P, Mangeot PE, Ricci EP, Mourad R, Haber JE, Noordermeer D, Legube G..
Loop extrusion as a mechanism for formation of DNA damage repair foci.
Nature
2021 Feb - Aline Marnef, Anne-Laure Finoux, Coline Arnould, Emmanuelle Guillou, Virginie Daburon, Vincent Rocher, Thomas Mangeat, Philippe E. Mangeot, Emiliano P. Ricci and Gaëlle Legube .
A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair
Genes and Development
2019 Aug - Puget N, Miller KM, Legube G.
Non-canonical DNA/RNA structures during Transcription-Coupled Double-Strand Break Repair: Roadblocks or Bona fide repair intermediates?
DNA repair
2019 Jul - Clouaire T, Legube G.
A Snapshot on the Cis Chromatin Response to DNA Double-Strand Breaks
Trends in Genetics
2019 May - Mangeot PE, Risson V, Fusil F, Marnef A, Laurent E, Blin J, Mournetas V, Massouridès E, Sohier TJM, Corbin A, Aubé F, Teixeira M, Pinset C, Schaeffer L, Legube G, Cosset FL, Verhoeyen E, Ohlmann T, Ricci EP.
Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins
Nature communications
2019 Jan - Clouaire T, Rocher V, Lashgari A, Arnould C, Aguirrebengoa M, Biernacka A, Skrzypczak M, Aymard F, Fongang B, Dojer N, Iacovoni JS, Rowicka M, Ginalski K, Côté J, Legube G.
Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures
Molecular Cell
2018 Oct - Full Publication List
2018 Aug - Mourad R, Ginalski K, Legube G, Cuvier O..
Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution.
Genome Biol
2018 Mar - Cohen S, Puget N, Lin YL, Clouaire T, Aguirrebengoa M, Rocher V, Pasero P, Canitrot Y, Legube G.
Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations.
Nature Communication
2018 Feb - Guénolé A, Legube G..
A meeting at risk: Unrepaired DSBs go for broke.
Nucleus
2017 Nov - Clouaire T, Marnef A, Legube G..
Taming Tricky DSBs: ATM on duty.
DNA repair
2017 Jun - Marnef A, Cohen S, Legube G..
Transcription-coupled DNA Double Strand Break repair: Active genes need special care.
J Mol Biol.
2017 Mar - Aymard F, Aguirrebengoa M, Guillou E, Javierre BM, Bugler B, Arnould C, Rocher V, Iacovoni JS, Biernacka A, Skrzypczak M, Ginalski K, Rowicka M, Fraser P, Legube G..
Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes.
Nat Struct Mol Biol
2017 Mar - Marnef A, Legube G..
Organizing DNA repair in the nucleus: DSBs hit the road.
Curr Opin Cell Biol.
2017 Jan - Caron P, Choudjaye J, Clouaire T, Bugler B, Daburon V, Aguirrebengoa M, Mangeat T, Iacovoni JS, Álvarez-Quilón A, Cortés-Ledesma F, Legube G..
Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks.
Cell Reports
2015 Nov . - Clouaire T, Legube G.
DNA double strand break repair pathway choice: a chromatin based decision?
Nucleus.
2015 Feb - Aymard F, Bugler B, Schmidt CK, Guillou E, Caron P, Briois S, Iacovoni JS, Daburon V, Miller KM, Jackson SP, Legube G..
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
Nat Struct Mol Biol.
2014 Apr - Lee CS, Lee K, Legube G, Haber JE.
Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break
Nat Struct Mol Biol
2014 Jan - Caron P, Aymard F, Iacovoni JS, Briois S, Canitrot Y, Bugler B, Massip L, Losada A, Legube G.
Cohesin protects genes against γH2AX Induced by DNA double-strand breaks
PLoS Genetics
2012 Jan - Iacovoni JS, Caron P, Lassadi I, Nicolas E, Massip L, Trouche D, Legube G.
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome.
EMBO Journal
2010 Apr
